Sean Patrick Flanery as Connor MacManus

Norman Reedus as Murphy MacManus

Billy Connolly as Poppa Il Duce

Clifton Collins Jr. as Romeo

Julie Benz as Eunice Bloom

Peter Fonda as The Roman

Paul Johansson as Rick

Judd Nelson as Concezio Yakavetta

David Della Rocco as Rocco

Bob Marley as Detective Greenly

Brian Mahoney as Detective Duffy

David Ferry as Detective Dolly

Gerard Parkes as Doc

Richard Fitzpatrick as The Chief

Robert Mauriell as Louie

Daniel DeSanto as Crew Cut

Robb Wells as Jimmy the Gofer

Pedro Salvín as Uncle Cesar

Dwayne McLean as Father McKinney

Tom Barnett as Irish Gun Dealer

Bob Rubin as Gorgeous George

Mairtin O'Carrigan as Father Sibeal

Sweeney MacArthur as Jacob McManus

Aaron Berg as Jo Jo Rhama

Joris Jarsky as Lloyd

Zachary Bennett as Roy

Willem Dafoe as Paul Smecker

Erika Bruun-Andersen as Massage Therapist

Matthew Chaffee as Officer Chaffey

Carlo Berardinucci as 50's Mafioso

Joe Parro as 50's Mafioso

Joseph Di Mambro as 50's Thug

Philip Bucceri as 50's Thug

Tony Munch as 50's Thug

Matthew G. Taylor as Giant

Paul De La Rosa as Cab Driver

Paulino Nunes as Capo

A. Frank Ruffo as Capo

Stefano DiMatteo as Capo

Marco Bianco as Capo

Paul Rapovski as Capo

Santino Buda as Capo

Jeremy Wright as Dock Worker

Darryl Flatman as G-Man

Darryl Pring as Hot Dog Vendor

Rolando Alvarez Giacoman as Mexican Seaman

Brad Davis as North Side Bruglione

Ermes Blarasin as North Side Bruglione

Flint Eagle as North Side Bruglione

Brian Frank as North Side Bruglione

Steve 'Shack' Shackleton as North Side Bruglione

Brendan Wall as North Side Bruglione

Shamus Fynes as Police Officer

Louis Di Bianco as Patronazzi

Louis Di Bianco as Pedestrian

George Nickolas K. as Pedestrian

Howard Hoover as Reporter #1

Joey Amorosino as Reporter #2

Mark Stables as Prison Guard

Jerry Azzopardi as FBI Agent

Brendan Carmody as Thug in the Woods

Scott Savitz as Street Interviewee

Paul Joyce as Street Interviewee

John Herman as Street Interviewee

Kara Apostolica as Street Interviewee

Kimberly Tuscano as Street Interviewee

Matthew Lemche as Noah (as Matt Lemche)