Tim Robbins as Jacob

Elizabeth Peña as Jezzie

Danny Aiello as Louis

Matt Craven as Michael

Pruitt Taylor Vince as Paul

Jason Alexander as Geary

Patricia Kalember as Sarah

Eriq La Salle as Frank

Ving Rhames as George

Brian Tarantina as Doug

Anthony Alessandro as Rod

Brent Hinkley as Jerry

S. Epatha Merkerson as Elsa

Suzanne Shepherd as Hospital Receptionist

Doug Barron as Group Leader

Jan Saint as Santa

Kisha Skinner as Street Singer

Dion Simmons as Street Singer

Sam Coppola as Taxi Driver

Patty Rosborough as Drunk

Evan O'Meara as Sam

Kyle Gass as Tony

Gloria Irizarry as Mrs. Carmichael

Lewis Black as Jacob's Doctor

Raymond Anthony Thomas as Policeman

Christopher John Fields as Field Medic

Jaime Perry as Field Medic

Michael Tomlinson as Field Doctor

A.M. Marxuach as Field Doctor

Antonia Rey as Woman on Subway

John Capodice as Army Officer

John P. 'Jack' McLaughlin as Army Officer

Bellina Logan as Emergency Ward Nurse

Scott Cohen as Resident Doctor

Davidson Thomson as Evil Doctor

Bryan Larkin as Jed

B.J. Donaldson as Eli

Thomas A. Carlin as Doorman

Carol Schneider as Nurse

Becky Ann Baker as Nurse

Diane Kagan as Nurse

Billie Neal as Della

Mike Stokie as Field Sergeant

James Ellis Reynolds as EMT Bearer

Dennis Rubin Green as Attendant

Brad Hamler as Orderly

Byron Minns as Orderly

Reggie McFadden as Partygoer

Stephanie Berry as Partygoer

Chris Murphy as Partygoer

John-Martin Green as Partygoer

Arleigh Richards as Paul's Wife

Ann Pearl Gary as Mourner

Barbara Gruen as Mourner

Joe Quintero as Street Kid

John Louis Fischer as Machine Gunner

Alva Williams as Masked Man

Elizabeth Abassi as Hospital Patient

Nora Burns as Hospital Patient

Alison Gordy as Hospital Patient

Jessica Roberts as Hospital Patient

Holly Kennedy as Hospital Patient

Blanche Irwin Stuart as Hospital Patient

Perry Lang as Jacob's Assailant

José Alvarez as Factory Worker (uncredited)

Robert Baglia as Tommy, Patient (uncredited)

Steve Baker as Pool Player (uncredited)

Orson Bean as Self - Game Show Panelist (archive footage) (uncredited)

Macaulay Culkin as Gabe (uncredited)

Ray DeFeis as Straight Jacket Patient (uncredited)

Ed Jupp Jr. as Eyeless Doctor (uncredited)