Paul Muni as Lee

Ann Dvorak as Josephine

Barton MacLane as Red Bastian

Robert Barrat as Dr. Ginder

John Eldredge as Dr. Burton

Hobart Cavanaugh as Stevens

Helen Lowell as Ma Ganson

Mayo Methot as Muggsy

Henry O'Neill as Greer

Grace Stafford as Caroline Suggs

Samuel S. Hinds as Dr. McClintick

June Travis as Dublin

Raymond Brown as Ben Suggs

Olin Howland as Bob Catlett

Joe Downing as Cinq Laval

Marie Astaire as Moll

Vangie Beilby as Effie

William Burress as George S. Harris - Grocery Proprietor

Glen Cavender as Townsman

Lucille Collins as Moll

Frank Darien as Sam - a Druggist

Hal K. Dawson as Mel Towne

James Donlan as Salesman in Car

Jimmie Dundee as Gangster

Bill Elliott as Tom Collins - Greer's Associate

Dick Elliott as Photographer

Jack Gardner as Photographer

Al K. Hall as Drunk

Otis Harlan as Fisher

Harry Harvey as Photographer

Ben Hendricks Jr. as Sentry at Catlett's House

Al Hill as Gangster in Car

Alfred P. James as Farmer

John Kelly as Al - a Gangster

Milton Kibbee as Bank Teller

Marc Lawrence as Lefty Croger - a Gangster

Ralph Lewis as Bookstore Proprietor

Jerry Madden as Excited Boy

June Martel as Young Woman

Frank McGlynn Jr. as Gangster

Larry McGrath as Gangster

Ivan Miller as Sheriff Ed Doolittle

Gene Morgan as Photographer

Adrian Morris as Beanie - a Gangster

Jack Norton as Drunk in Park

Henry Otho as Gangster

Paul Panzer as Townsman at Celebration Party

Bob Perry as Gangster

Ralph Remley as Bill Payne - a Townsman

Kathryn Sheldon as Woman Talking to Stout Woman

Carl Stockdale as Abner Cluett - a Townsman

Charles Sullivan as Gangster

Grady Sutton as Grocery Clerk

Emerson Treacy as Young Man

Maidel Turner as Mary

Max Wagner as Gangster

Lucille Ward as Stout Woman Outside of Dr. Cardwell's

Billy Wayne as Dave - a Townsman

Huey White as Drunk

Leo White as Tailor

Tom Wilson as Clem - a Townsman

Sam Wren as Chuck