Bruce Willis as Omar

Jason Patric as Paul

John Cusack as Sam

Jessica Lowndes as Angela

Gia Mantegna as Beth

Rain as Mark

50 Cent as The Pharmacy

Don Harvey as Riley

Jesse Pruett as Wilson

Didi Costine as Rachel

Bonnie Somerville as Susan

Tim Fields as Jimmy

Andréa Burns as Janine

Jim Bennett as Justin

Johnathon Schaech as Frank

Tyler Jon Olson as Eddie

Jonathan Carkeek as Mitch

Jay Oringer as Brickyard Bouncer

Tara Holt as Candice

Andrew Wert as Facetime Stranger

Danielle Phelan as Junky Girlfriend

David Gordon as Omar's Head of Security

Martin Blencowe as Bartender

Courtney Blythe Turk as Meagan

Natalie Light as Sara (uncredited)

Pak Ho-Sung as Hotel Clerk (uncredited)