Bob Hope as Sidney Melbourne (The Lemon Drop Kid)

Marilyn Maxwell as 'Brainey' Baxter

Lloyd Nolan as Oxford Charley

Jane Darwell as 'Nellie Thursday' Regan

Andrea King as Stella

Fred Clark as Moose Moran

Jay C. Flippen as Straight Flush Tony

William Frawley as Gloomy Willie

Harry Bellaver as Sam the Surgeon

Sid Melton as Little Louie

Ben Welden as Singing Solly

Ida Moore as Mrs. Feeney - The Bird Lady

Francis Pierlot as Henry Regan

Charles Cooley as Goomba

Salvatore De Lorenzo as Street-corner Santa Claus

Harry Shannon as John (Policeman)

Bernard Szold as Honest Harry

Tor Johnson as Super Swedish Angel (Wrestler)

Tom Dugan as No Thumbs Charlie

Stanley Andrews as Judge Wilkinson (uncredited)

Billie Bird as Racetrack Bettor on Iron Bar (uncredited)

Oliver Blake as Racetrack Bettor on Iron Bar (uncredited)

John Doucette as Muscleman (uncredited)

Pat Flaherty as Police Captain Swain (uncredited)

Charmienne Harker as Dancer (uncredited)

Jack Kruschen as Muscleman (uncredited)

Mary Moder as Holly Seller (uncredited)

Mary Murphy as Girl (uncredited)

Bruce Riley as Clerk (uncredited)

Anthony Warde as Thoughtful Man (uncredited)