Danny Glover as George Knox

Tony Danza as Mel Clark

Brenda Fricker as Maggie Nelson

Ben Johnson as Hank Murphy

Joseph Gordon-Levitt as Roger

Jay O. Sanders as Ranch Wilder

Taylor Negron as David Montagne

Milton Davis Jr. as J.P.

Christopher Lloyd as Al the Angel

Tony Longo as Triscuit Messmer

Neal McDonough as Whitt Bass

Stoney Jackson as Ray Mitchell

Matthew McConaughey as Ben Williams

Adrien Brody as Danny Hemmerling

Tim Conlon as Wally

Israel Juarbe as Jose Martinez

Albert Alexander Garcia as Pablo Garcia

Dermot Mulroney as Roger's Father

Robert Clohessy as Frank Gates

Connie Craig as Carolyn

Johnathan Proby as Miguel

Michael Halton as Hairy Man

Mark Conlon as Photographer

Danny Walcoff as Marvin

James C. King as Home Plate Umpire

Tony Reitano as Singing Umpire

Diane Amos as Woman Next to J.P.

Christopher Leon DiBiase as Teenager

Robert Stuart Reed as Guard

Ruth Beckford as Judge

Victoria Skerritt as Social Worker

Devon Dear as National Anthem Singer

O.B. Babbs as Angels Player (Mapel)

Mitchell Page as Angels Player (Abascal)

Mark Cole as Angels Player (Norton)

Chuck Dorsett as Usher

Carney Lansford as Kesey

Pamela West as Ms. Angel

Oliver Dear as Rookie Angel

Lionel Douglass as Brother Angel

Bundy Chanock as Umpire

John Howard Swain as First Base Umpire

Marc Magdaleno as Home Plate Umpire #2

Ron Roggé as Angels Coach

Steven Meredith as Toronto Player

William Dear as Toronto Manager