James Mason as Ed Avery

Barbara Rush as Lou Avery

Walter Matthau as Wally Gibbs

Robert F. Simon as Dr. Norton

Christopher Olsen as Richie Avery

Roland Winters as Dr. Ruric

Rusty Lane as Bob LaPorte

Rachel Stephens as Nurse

Kipp Hamilton as Pat Wade

Betty Caulfield as Mrs. LaPorte (uncredited)

Virginia Carroll as Mrs. Jones (uncredited)

Renny McEvoy as Mr. Jones (uncredited)

Billy Jones as Mr. Byron (uncredited)

Dee Aaker as Joe (uncredited)

Jerry Mathers as Freddie (uncredited)

Portland Mason as Nancy (uncredited)

Natalie Masters as Mrs. Tyndall (uncredited)

Richard Collier as Milkman (uncredited)

Lewis Charles as Mr. McLennan (uncredited)

Gus Schilling as Druggist (uncredited)

Alex Frazer as Clergyman (uncredited)

Mary McAdoo as Mrs. Edwards (uncredited)

Mary Carver as Saleslady (uncredited)

Eugenia Paul as Saleslady (uncredited)

Gladys Richards as Lab Nurse (uncredited)

David Bedell as X-Ray Doctor (uncredited)

Joseph Mell as Dispatcher (uncredited)

George Chester as Janitor (uncredited)