Lando Buzzanca as Primo fidanzato di Margherita

Igli Villani as Margherita Bragone

Fred Robsahm as Raffaello Sanzio

Erminio Macario as Don Giacinto

Carlo Dapporto as Comandante Guardie Svizzere

Francesco Mulè as Papa Leone X

Ira von Fürstenberg as Principessa Beatrice del Giovenale

Sydney Chaplin as Melozzo

Vittorio Caprioli as Messer Anticoli

Checco Durante as fornaio Bragone

Franco Franchi as Carceriere

Ciccio Ingrassia as Carceriere

Mario Carotenuto as Il Bargello

Umberto D'Orsi as Cardinale Ruffo

Franca Valeri as Vedova Anticoli

Gino Bramieri as Il 'fratellone della Buona Morte'

Enrico Luzi as Discepolo di Raffaello

Enzo Guarini as Discepolo di Raffaello

Lino Banfi as Discepolo di Raffaello

Gianfranco D'Angelo as Discepolo di Raffaello

Pino Ferrara as

Rosita Pisano as

Mimma Amendola as

Vasco Santoni as

Andrea Aureli as

Mimmo Poli as

Otello Belardi as

Carlo Pisacane as Avvocato difensore d'ufficio

Stefano Oppedisano as

Paolo Panelli as Cliente osteria