Richard Gere as Off. Eddie Dugan

Don Cheadle as Det. Clarence 'Tango' Butler

Ethan Hawke as Det. Sal Procida

Wesley Snipes as Casanova 'Caz' Phillips

Vincent D'Onofrio as Bobby 'Carlo' Powers

Ellen Barkin as Agent Smith

Michael Kenneth Williams as Red

Shannon Kane as Chantel

Brían F. O'Byrne as Det. Ronny Rosario

Will Patton as Lt. Bill Hobarts

Lili Taylor as Angela Procida

Wass Stevens as Det. Patrick Leary

Armando Riesco as Det. George Montress

Wade Allain-Marcus as C-Rayz

Logan Marshall-Green as Melvin Panton

Jesse Williams as E. Quinlan

Hassan Johnson as Beamer

Jas Anderson as K. Rock

John D'Leo as Vinny

Stella Maeve as Cynthia

Raquel Castro as Katherine

Robert John Burke as State Trooper #1

Cle Sloan as

Bruce MacVittie as Father Scarpitta (as Bruce Macvittie)

Sarah Thompson as Sarie

Thomas Jefferson Byrd as Uncle Jeb

Lela Rochon as Investigator #1 (as Lela Rochon Fuqua)

Ed Moran as Investigator #2

Isiah Whitlock, Jr. as Investigator #3 (as Isiah Whitlock)

Tawny Cypress as Allisa

Frank Anello as NYPD Officer (uncredited)