Peter Cushing as Dr. Sandor Schreck aka "Dr. Terror"

Christopher Lee as Franklyn Marsh

Roy Castle as Biff Bailey

Alan Freeman as Bill Rogers

Donald Sutherland as Bob Carroll

Neil McCallum as Jim Dawson

Bernard Lee as Hopkins (segment 2 "Creeping Vine")

Peter Madden as Caleb (segment 1 "Werewolf")

Ursula Howells as Mrs. Deirdre Biddulph (segment 1 "Werewolf")

Katy Wild as Valda (segment 1 "Werewolf")

Edward Underdown as Tod (segment 1 "Werewolf")

Ann Bell as Ann Rogers (segment "Creeping Vine")

Jeremy Kemp as Jerry Drake (segment 2 "Creeping Vine")

Phoebe Nicholls as Carol Rogers (segment 2 "Creeping Vine")

Kenny Lynch as Sammy Coin (segment 3 "Voodoo")

Harold Lang as Roy Shine (segment 3 "Voodoo")

Christopher Carlos as Vrim (segment 3 "Voodoo")

Max Adrian as Dr. Blake (segment 5 "Vampire")

Jennifer Jayne as Nicolle (segment 5 "Vampire")

Michael Gough as Eric Landor (segment 4 "Disembodied Hand")

Isla Blair as Pretty Girl (segment 4 "Disembodied Hand")

Frank Barry as Dambala (segment 3 "Voodoo")

Judy Cornwell as Nurse (segment 4 "Disembodied Hand")

Frank Forsyth as Toastmaster (segment 4 "Disembodied Hand")

Caron Gardner as Joo Joo Club Patron (segment 3 "Voodoo")

Kenneth Kove as Third Male Friend (segment 4 "Disembodied Hand")

Thomas Baptiste as Dambala (Segment 3 "Voodoo")

Al Mulock as Detective (segment 5 "Vampire")

Walter Sparrow as Second Ambulance Man (segment 4 "Disembodied Hand")

Hedger Wallace as Surgeon (segment 4 "Disembodied Hand")

Brian Hankins as George (segment 4 "Disembodied Hand")

Faith Kent as Lady in Art Gallery (segment 4 "Disembodied Hand")

Laurie Leigh as Nurse (segment 5 "Vampire")

Irene Richmond as Mrs Ellis (segment 5 "Vampire")

Valerie St. Clair as Cigarette Girl (segment 3 "Voodoo")