Michelle Williams as Anna Watson

Meat Loaf as Billy

Tim Guinee as Tom

Louis Zorich as Sammy

Bill Raymond as Dr. Harold Ashton

Wendell Pierce as Dan

Merritt Wever as Betty

Jonathan Watton as Bobby Watson

Ileen Getz as Nurse Aphrodite

John Paul Tremblay as Moe

Robb Wells as Joe

Heidi von Palleske as Cindy Watson

Jeremy Akerman as Robert Watson Sr.

Gerry Mendicino as Johnnie

John Dunsworth as Pastor

Paul Macleod as Preacher

Meaghan Hutchison as Dopnna Frankel

Rhonda McLean as Jane Frankel

Bruce Graham as Frank Frankel

Gary Levert as Mental Health Visitor

Dennis Brown as Herman

Mark A. Owen as Bartender

Shaun Clarke as Tony the Toastmaster

Mike Smith as Lobotomy Patient

Mark Day as Mark (uncredited)

Marcus Shultz as Bartender #2 (uncredited)