Stephen Tyrone Williams as Dr. Hess Green

Zaraah Abrahams as Ganja Hightower

Rami Malek as Seneschal Higginbottom

Elvis Nolasco as Lafayette Hightower

Thomas Jefferson Byrd as Bishop Zee

Joie Lee as Nurse Colquitt

Felicia Pearson as Lucky Mays

Steven Hauck as Dr. Wood

Lauren Macklin as Nurse Royster

Stephen McKinley Henderson as Deacon Yancy

Jeni Perillo as Sahara Paysinger

Katherine Borowitz as Ms. Staples

Donna Dixon as Ms. Blair

Chiz Schultz as Dr. Redding

Rafael Osorio as Doorman Clemente

Cinqué Lee as Ellington Christopher

Lil Buck as Jookin' Dancer

Naté Bova as Tangier Chancellor

Al Palagonia as Jet Concierge / Dom Pagnotti

Quincy Tyler Bernstine as Usherette / Sister Hazel

Kayinde J. Harris as Usherette / Sister Gwen

Siedah Garrett as Private Jet Stewardess