Jaime Pressly as Alyson Simon

Kylie Rogers as Claire Simon

Tobin Bell as Dr. Freeman

Patrick Muldoon as Jonathan Simon

Mark DeCarlo as Ken Stevens

Justina Machado as Prof. Elena Carranza

Lauren K. Montgomery as Ofelia

Marina Sirtis as Janine

Scott Thomas Reynolds as Danny

Tracy Mulholland as Jane

Rio Mangini as Dylan

Trilby Glover as Kathy

Mary Pat Gleason as Carol

Joey Luthman as Zachary

Gabe O'Mara as Zachary age 10

Kristen Kerr as Nurse

Mercy Malick as Officer Adrien