Gene Wilder as Sigerson Holmes

Madeline Kahn as Jenny Hill

Marty Feldman as Sgt. Orville Stanley Sacker

Dom DeLuise as Eduardo Gambetti

Leo McKern as Moriarty

Roy Kinnear as Moriarty's Assistant

John Le Mesurier as Lord Redcliff

Douglas Wilmer as Sherlock Holmes

Michael Crane as Renato

Albert Finney as Man in Audience at Opera

Thorley Walters as Dr. Watson

George Silver as Bruner

Nicholas Smith as Hunkston

John Hollis as Moriarty's Gunman

Aubrey Morris as Coach Driver

Tommy Godfrey as Fred

Susan Field as Queen Victoria

Wolfe Morris as Frenchman

Julian Orchard as Man in Tails

Kenneth Benda as Butler

Mel Brooks as Lion victim (voice)

Joseph Behrmannis as Russian

Tony Sympson as Opera Conductor