Melanie Griffith as Patty Palmer

Matthew Modine as Drake Goodman

Michael Keaton as Carter Hayes / James Danforth

Mako as Toshio Watanabe

Nobu McCarthy as Mira Watanabe

Laurie Metcalf as Stephanie MacDonald

Carl Lumbly as Lieutenant Lou Baker

Dorian Harewood as Dennis

Luca Bercovici as Greg

Tippi Hedren as Florence Peters

Sheila McCarthy as Liz Hamilton

Guy Boyd as Warning Cop

Jerry Hardin as Bennett Fidlow

Dan Hedaya as Loan Officer

James Staley as District Attorney Henry

Miriam Margolyes as Realtor

Takayo Fischer as Bank Teller

Frank DiElsi as Precinct Cop

Luis Oropeza as Revilla

F. William Parker as Judge Mitchell Black

Nicholas Pryor as Hotel Front Office Manager Neil Spisak

Tony Simotes as Desk Clerk Victor

O-Lan Jones as Motel Maid Patricia

Seth Isler as Sergeant Bobby Amato

Dabbs Greer as Mr. Thayer

Florence Sundstrom as Mrs. Thayer

Noel Evangelisti as Mrs. Smith

Nick Rutherford as Child

Tim Pulice as Younger Man

Ray Hanis as Older Man

Tom Nolan as Bank Teller

Daniel MacDonald as George

J.P. Bumstead as 1st Deputy Sheriff

Hal Landon Jr. as 2nd Deputy Sheriff

Hy Anzell as Locksmith Manford Bagel

Tracey Walter as Exterminator

William Paterson as Mr. Hill

D.W. Moffett as Bill

Barbara Tyson as Amy

John Diaz as Shoe Shine Man

Roger Bearde as Arresting Cop

Ed Hodson as Other Cop

Michael Parker as Man at Police Station

Maggy Myers Davidson as Diamond Lady

Bud Ekins as Thug

Danny Wynands as Thug

David Lloyd Wilson as Television Host

Matthew Flint as Neighbor

Scott Freeman as Neighbor

Alice Barden as Neighbor

Danny Kovacs as Neighbor

Wat Takeshita as Neighbor

Frank Maruoka as Neighbor

Tohoru Masamune as Neighbor

Aida Anderson as Neighbor

Linda Austin as Neighbor

Beverly D'Angelo as Ann Miller (uncredited)

John Schlesinger as Man in Elevator (uncredited)