John Wayne as John Chance

Dean Martin as Dude

Ricky Nelson as Colorado Ryan

Angie Dickinson as Feathers

Walter Brennan as Stumpy

Ward Bond as Pat Wheeler

John Russell as Nathan Burdette

Pedro Gonzalez Gonzalez as Carlos Robante

Estelita Rodriguez as Consuela Robante

Claude Akins as Joe Burdette

Malcolm Atterbury as Jake

Harry Carey, Jr. as Harold

Walter Barnes as Charlie (uncredited)

George Bell as Barfly (uncredited)

Noble 'Kid' Chissell as Barfly (uncredited)

Cecil Combs as Barfly (uncredited)

Myron Healey as Barfly (uncredited)

Cactus Mack as Barfly (uncredited)

Mathew McCue as Barfly (uncredited)

Frank Mills as Barfly (uncredited)

Kansas Moehring as Barfly (uncredited)

Jack Perry as Barfly (uncredited)

Danny Sands as Barfly (uncredited)

Sailor Vincent as Barfly (uncredited)

Bob Whitney as Barfly (uncredited)

Nesdon Booth as (uncredited)

Robert Donner as (uncredited)

Ted White as (uncredited)

George Bruggeman as Clem (uncredited)

Buck Bucko as Barber (uncredited)

Yakima Canutt as Gunman on Horse (uncredited)

Chuck Roberson as Gunman (uncredited)

Albert Cavens as Henchman (uncredited)

Tom Monroe as Henchman (uncredited)

Fred Graham as 2nd Burdette Man in Shootout (uncredited)

Eugene Iglesias as 1st Burdette Man in Shootout (uncredited)

Joe Gray as Card Player (uncredited)

Dean Smith as Card-Playing Burdette Henchman (uncredited)

Riley Hill as Messenger (uncredited)

Richard LaMarr as Minor Role (uncredited)

Gordon Mitchell as Bar Cowboy Watching Fistfight (uncredited)

Bob Reeves as Bartender (uncredited)

Bing Russell as Cowboy Murdered in Saloon (uncredited)

Bob Steele as Matt Harris (uncredited)

Bud Cokes as Barfly (uncredited)

David O. McCall as Bartender (uncredited)