George Clooney as Lee Gates

Julia Roberts as Patty Fenn

Jack O'Connell as Kyle Budwell

Dominic West as Walt Camby

Caitríona Balfe as Diane Lester

Giancarlo Esposito as Captain Powell

Christopher Denham as Ron Sprecher

Lenny Venito as Lenny Libatino

Chris Bauer as Lt. Nelson

Dennis Boutsikaris as Avery Goodloe CFO

Emily Meade as Molly

Dola Rashad as Bree

Aaron Yoo as Won Joon

Carsey Walker Jr. as Tech Sam

Grant Rosenmeyer as Dave

Jim Warden as Technical Director Jim

Joseph D. Reitman as Matty (Floor Manager)

Olivia Luccardi as Arlene

Grizz Chapman as Network Security Guard

Robert C. Kirk as Security Officer Nolan

Genevieve Adams as Production Assistant

Daoud Heidami as Freddy (Previous Host)

Anthony DeSando as Officer Benson

Ivan Martin as Lt. Vasquez

John Ventimiglia as A Team Leader

Dominic Colón as NYPD Detective

Chad Jennings as ESU Officer

Cliff Moylan as Sgt O'Donnell

Brian Edwards as Police Officer

Jimmy Gary Jr. as NYPD Officer #1

Frantzy Orisma as NYPD Officer #2

Greta Lee as Amy

Charlie Thurston as Ryan (Diane's Assistant)

Patricia Dunnock as Marta (Secretary)

Sahr Ngaujah as Yao Appiah COO

Vernon Campbell as Andre (IBIS Security Guard)

Daniel K. Isaac as Male Raver

Darri Ingolfsson as Joji

Makhaola Ndebele as Moshe Mambo

Jamar Greene as Blue Collar Customer

Rob Falcone as Blue Collar Mechanic

Bobby Kruger as Stockbroker

David Healy as News Anchor

Matt Walton as An Anchorman

Pun Bandhu as Yet Another Anchorman

Jake Choi as Korean News Anchor

Nick Boraine as British Reporter

Jeff Witzke as TV Reporter

Bryan Burton as Teenage Boy #2

Frank Pando as Guy on Street

Shauna Mitchell as Dancer #2

Tanisha Scott as Dancer

Cenk Uygur as Self

Wolf Blitzer as Self (uncredited)

Pat Kiernan as Self (uncredited)

Nick Calderone as Co-Host of Right This Minute (uncredited)

Christian Vera as Co-Host of Right This Minute (uncredited)

Gayle Bass as Co-Host of Right This Minute (uncredited)

Charity Bailey as Co-Host of Right This Minute (uncredited)

Oli Pettigrew as Co-Host of Right This Minute (uncredited)

Robert Reich as Self (archive footage) (uncredited)