William Powell as Andrew Gentling

Shelley Winters as Catherine Sykes

Marsha Hunt as Martha Wier

Dorothy Hart as Helen Gentling

James Gleason as Captain Gledhill

Felix Bressart as Professor Morris Avrum

Art Baker as Henry Pritchard

Sheldon Leonard as Detective Pacciano

Howard Freeman as Dr. Markheim

Houseley Stevenson as Montgomery Thatcher

Paul Harvey as Mr. Arnspiger

Francis Pierlot as Dr. Herbert Watson

Jess Barker as Arnold Sykes

Mikel Conrad as Freddie Blair

Vangie Beilby as Old Lady at Lecture (uncredited)

Marjorie Bennett as Waitress (uncredited)

Leonard Bremen as Truck Driver (uncredited)

Paul Brinegar as Reporter (uncredited)

Frank Cady as Reporter (uncredited)

Edmund Cobb as Policeman (uncredited)

Helen Crozier as Maid (uncredited)

Johnny Duncan as Bellhop (uncredited)

Adolph Faylauer as Bald Man at Lecture (uncredited)

Sandra Gould as Newspaper Girl (uncredited)

Ethyl May Halls as Woman at Window (uncredited)

Chuck Hamilton as Policeman (uncredited)

Herbert Heywood as Attendant (uncredited)

Tommy Ivo as Horace - Boy at Roadblock (uncredited)

Lyle Latell as Reporter (uncredited)

George Lynn as Policeman (uncredited)

Enid Markey as Clara (uncredited)

Maurice Marsac as Louis (uncredited)

Charles McAvoy as Policeman (uncredited)

Ralph Peters as Portly Man (uncredited)

Jack Rice as Good Humor Man (uncredited)

Brick Sullivan as Policeman (uncredited)

Charles Sullivan as Truck Driver in Cafe (uncredited)

Jim Toney as Bartender (uncredited)

Harland Tucker as Clerk (uncredited)

Minerva Urecal as Gas Station Attendant (uncredited)

Dorothy Vaughan as Leona (uncredited)

Charles Flynn as Policeman (uncredited)