Henry Fonda as Wyatt Earp

Linda Darnell as Chihuahua

Victor Mature as Dr. John 'Doc' Holliday

Cathy Downs as Clementine Carter

Walter Brennan as Old Man Clanton

Tim Holt as Virgil Earp

Ward Bond as Morgan Earp

Alan Mowbray as Granville Thorndyke

John Ireland as Billy Clanton

Roy Roberts as Mayor

Jane Darwell as Kate Nelson

Grant Withers as Ike Clanton

J. Farrell MacDonald as Mac the barman

Russell Simpson as John Simpson

Robert Adler as Stagecoach Driver (uncredited)

C.E. Anderson as Townsman (uncredited)

Don Barclay as Opera House Owner (uncredited)

Hank Bell as Opera House Patron (uncredited)

Danny Borzage as Accordionist (uncredited)

Ruth Clifford as Opera House Patron (uncredited)

Frank Conlan as Pianist (uncredited)

Tex Cooper as Townsman (uncredited)

Jack Curtis as Bartender (uncredited)

William B. Davidson as Saloon Owner (uncredited)

James Dime as Vaquero (uncredited)

Tex Driscoll as Townsman (uncredited)

Frank Ellis as Barfly (uncredited)

Francis Ford as Dad - Old Soldier (uncredited)

Earle Foxe as Gambler (uncredited)

Don Garner as James Earp (uncredited)

Ben Hall as Barber (uncredited)

Aleth Hansen as Guitarist (uncredited)

Jack Kenny as Barfly (uncredited)

Duke R. Lee as Townsman (uncredited)

Fred Libby as Phin Clanton (uncredited)

Mae Marsh as Simpson's Sister (uncredited)

Margarita Martín as Woman (uncredited)

Kermit Maynard as Barfly (uncredited)

Louis Mercier as François - the Chef (uncredited)

Jack Montgomery as Faro Dealer (uncredited)

Jack Pennick as Stagecoach Driver (uncredited)

Mickey Simpson as Sam Clanton (uncredited)

Charles Stevens as Indian Charlie (uncredited)

Arthur Walsh as Hotel Clerk (uncredited)

Harry Woods as Luke (uncredited)