Alan Ladd as Shane

Jean Arthur as Marian Starrett

Van Heflin as Joe Starrett

Brandon De Wilde as Joey Starrett

Jack Palance as Jack Wilson

Ben Johnson as Chris Calloway

Edgar Buchanan as Fred Lewis

Emile Meyer as Rufus Ryker

Elisha Cook Jr. as Frank 'Stonewall' Torrey

Douglas Spencer as Axel 'Swede' Shipstead

John Dierkes as Morgan Ryker

Ellen Corby as Liz Torrey

Paul McVey as Sam Grafton

John Miller as Bartender Will Atkey

Edith Evanson as Mrs. Shipstead

Leonard Strong as Ernie Wright

Ray Spiker as Axel Johnson

Janice Carroll as Susan Lewis

Martin Mason as Ed Howells

Helen Brown as Martha Lewis

Nancy Kulp as Mrs. Howells

Ewing Miles Brown as Ryker Man (uncredited)

Bill Cartledge as Ryker Man (uncredited)

Chick Hannan as Ryker Man (uncredited)

George J. Lewis as Ryker Man (uncredited)

Jack Sterling as Ryker Man (uncredited)

Henry Wills as Ryker Man (uncredited)

Alana Ladd as Little Girl (uncredited)

David Ladd as Little Boy (uncredited)

Howard Negley as Yank Potts (uncredited)

Charles Quirk as Clerk (uncredited)

George Stevens as Knock Him Into That Pigpen, Chris! (voice) (uncredited)

Beverly Washburn as Ruth Lewis (uncredited)