Jon Voight as Joe Buck

Dustin Hoffman as Enrico "Ratso" Rizzo

Sylvia Miles as Cass

John McGiver as Mr. O'Daniel

Brenda Vaccaro as Shirley

Barnard Hughes as Towny

Ruth White as Sally Buck

Jennifer Salt as Annie

Gilman Rankin as Woodsy Niles

Gary Owens as Little Joe

T. Tom Marlow as Little Joe

George Eppersen as Ralph

Al Scott as Cafeteria Manager

Linda Davis as Mother on the Bus

J.T. Masters as Old Cow-Hand

Arlene Reeder as The Old Lady

Georgann Johnson as Rich Lady

Jonathan Kramer as Jackie

Anthony Holland as TV Bishop

Bob Balaban as The Young Student

Jan Tice as Freaked-Out Lady

Paul Benjamin as Bartender

Peter Scalia as Vegetable Grocer

Vito Siracusa as Vegetable Grocer

Peter Zamagias as Hat Shop Owner

Arthur Anderson as Hotel Clerk

Tina Scala as Laundromat Lady

Alma Felix as Laundromat Lady

Richard Clarke as Escort Service Man

Ann Thomas as The Frantic Lady

Viva as Gretel McAlbertson

Paul Rossilli as Hansel McAlbertson

Ultra Violet as The Party

Paul Jabara as The Party

International Velvet as The Party

Cecelia Lipson as The Party

Taylor Mead as The Party

Paul Morrissey as The Party

Joan Murphy as The Waitress

Al Stetson as Bus Driver

M. Emmet Walsh as Bus Passenger (uncredited)

Sandy Duncan as Woman in TV Montage (uncredited)

Philip Bruns as Man in TV Montage (uncredited)

Waldo Salt as Joe Pyne on TV Show (uncredited)

Bill Walters as St. Bernard Owner (uncredited)

Jay Morran as Pimp (uncredited)

Renee Semes as Hippie in Coffee Shop (uncredited)

Jeffrey Walker as Hippie (uncredited)

Mary Boylan as Old Lady in Subway (uncredited)

Marlene Clark as Party Guest (uncredited)

Paul Jasmin as Party Guest (uncredited)

Pat Ast as Party Guest (uncredited)

Randall Carver as Rapist in Flashback (uncredited)

Robert Dahdah as Bus Passenger (uncredited)

Trent Gough as Man at Lunch Counter (uncredited)

Larry Sherman as Homeless Man (uncredited)

Barbara Maggio as Gina (uncredited)

James Miller as Cowboy (uncredited)

Lucian Addario as Sailor in Bar (uncredited)

William Door as Man at Party (uncredited)