Walter Huston as Sam Dodsworth

Ruth Chatterton as Fran Dodsworth

Paul Lukas as Arnold Iselin

Mary Astor as Edith Cortright

David Niven as Captain Clyde Lockert

Gregory Gaye as Baron Kurt Von Obersdorf

Maria Ouspenskaya as Baroness Von Obersdorf

Odette Myrtil as Renée de Penable

Spring Byington as Matey Pearson

Harlan Briggs as Tubby Pearson

Kathryn Marlowe as Emily Dodsworth McKee

John Payne as Harry McKee

Bobby Barber as Italian Taxi Driver (Uncredited)

Wilson Benge as Steward on Queen Mary (Uncredited)

Ted Billings as Man on Railroad Platform (Uncredited)

Eugene Borden as Baggage Carrier at Train Station (Uncredited)

Horace B. Carpenter as Motor Company Employee (Uncredited)

Gino Corrado as American Express Clerk (Uncredited)

Jean De Briac as Official (Uncredited)

Helen Dickson as Tourist (Uncredited)

Jack George as Orchestra Leader in Vienna (Uncredited)

Fred Malatesta as Waiter (Uncredited)

Beatrice Maude as Mary (Uncredited)

Louis Mercier as French Railroad Conductor (Uncredited)

Inez Palange as Teresa (Uncredited)

John Picorri as Clerk (Uncredited)

Pat Somerset as Englishman (Uncredited)

William Wyler as Violin Player in Dance Orchestra (Uncredited)

Sam Harris as Ship Passenger (Uncredited)

John Barclay as Ship Passenger (Uncredited)

Steve Carruthers as Ship Passenger (Uncredited)

Bess Flowers as Ship Passenger (Uncredited)

J.C. Fowler as Ship Passenger (Uncredited)

Herschel Graham as Ship Passenger (Uncredited)

Loretta Russell as Ship Passenger (Uncredited)

Alphonse Martell as Ship Passenger (Uncredited)

Edmund Mortimer as Ship Passenger (Uncredited)

Harold Miller as Ship Passenger (Uncredited)

George Nardelli as Ship Passenger (Uncredited)

Dale Van Sickel as Ship Passenger (Uncredited)