Mark Blankfield as Bob Frankenheimer alias Bob Frankenstein

Leslie Jordan as Iggy

Jonathan Farwell as Dr. Frank Reutgar

Kathy Shower as Dr. Alice Singleton

Irwin Keyes as The Monster

Hamilton Mitchell as Dr. Dixon

Lou Cutell as Dr. Saperstein

Katie Caple as Verna

Dorothy Patterson as Mildred Pennys

Mark DeCarlo as Dr. Skip

Bunky Jones as Elizabeth Rice (as Rebunkah Jones)

Joleen Lutz as Candy Striper Patty

Ben Stein as Dr. Who

Bobby Pickett as Man in Elevator