Zac Efron as Dave Stangle

Adam Devine as Mike Stangle

Anna Kendrick as Alice

Aubrey Plaza as Tatiana

Sam Richardson as Eric

Stephen Root as Burt

Sugar Lyn Beard as Jeanie Stangle

Branscombe Richmond as Kalani - BBQ Chef

Marc Maron as Randy

Jake Johnson as Ronnie

Kumail Nanjiani as Keanu

Eugene Cordero as Kai - Hotel Manager

Mary Holland as Becky

Nicole Byer as Office Nicole

Stephanie Allynne as Office Stephanie

Chloe Bridges as Apartment Chloe

Stephanie Faracy as Rosie

Alice Wetterlund as Cousin Terry

Lavell Crawford as Keith

Erik Griffin as Driver

Jake Szymanski as Stable Guy

Wendy Williams as Wendy Williams

Kyle Smigielski as Luke

Andrea Miceli as Twin Sister #1

Nancy Miceli as Twin Sister #2

Christina Souza as Call Girl

Olga Kalashnikova as Russian Call Girl

Ashley Hobbs as White Supremacist Girl

Julia Fae as Grungy Girl #1

Andrea Russett as Grungy Girl #2

Danielle Zalopany as Militant Girl #1

Tabitha Humphrey as Militant Girl #2

Bob Turton as Bob / Lauralie

Jennie Pierson as Office Jennie

Hilty Bowen as Café Hilty

Tanisha Long as Café Tanisha

Cass Buggé as Apartment Cass

Ayden Mayeri as Apartment Ayden

Liberté Chan as Local Newscaster

Sandra Davis as Sandra

Jessika Van as Jessika the Girl in Street

Don Pomes as Grandpa Stangle

Sally Jackson as Grandma Stangle

Rory Hart as Frat Dude

Katherine Klosterman as Anniversary Montage Girl

Michael C. Price as Father Mike

Paula Fuga as Reception Singer

John Cruz as Rough Rider Singer

Henry Kapono Ka'aihue as Rough Rider Singer

Brother Noland as Rough Rider Singer

Kimee Balmilero as Weird Girl #1 (uncredited)

Margo Kazaryan as Pedestrian (uncredited)