Darren McGavin as Carl Kolchak

Jo Ann Pflug as Louise Harper

Simon Oakland as Tony Vincenzo

Scott Brady as Capt. Schubert

Wally Cox as Mr. Berry

Margaret Hamilton as Prof. Crabwell

Richard Anderson as Dr. Richard Malcolm

John Carradine as Llewellyn Crossbinder

Al Lewis as Tramp

Nina Wayne as Charisma Beauty

Virginia Peters as Wilma Krankheimer

Kate Murtagh as Janie Watkins

Ivor Francis as Dr. Webb

Diane Shalet as Joyce Gabriel

Anne Randall as Policewoman Sheila

Francoise Birnheim as Restaurant Woman

Regina Parton as Merissa (Ethel Parker)

David Armstrong as Police Officer (uncredited)

Margaret Bacon as Reporter (uncredited)

Al Beaudine as Reporter (uncredited)

Loren Brown as Bar Patron (uncredited)

Bill Clark as Bar Patron (uncredited)

Robert Cole as Reporter (uncredited)

Tony Dante as Reporter (uncredited)

George DiCenzo as Underground Tour Guide (uncredited)

Rudy Doucette as Man on Tour (uncredited)

Bob Harks as Bar Patron (uncredited)

Chester Hayes as Bar Patron (uncredited)

Bill McLean as Charlie the Bartender (uncredited)

Joe Phillips as Detective (uncredited)

Al Roberts as Police Officer (uncredited)

Arnold Roberts as Reporter (uncredited)

Hank Robinson as Police Officer (uncredited)

Bob Templeton as Bar Patron (uncredited)

George Tracy as Bar Patron (uncredited)

George Washburn as Police Officer (uncredited)