James Bolam as Harold Shipman

James Hazeldine as DI Stan Egerton

Olive Pendleton as Kathleen Grundy

Veda Warwick as May Clarke

Jacqueline Pilton as Primrose Shipman

Peter Gunn as DS John Ashley

Clare Kerrigan as Julie

Mary MacLeod as Ivy Lomas

Siobhan Finneran as Kathleen Adanski

Alan Rothwell as Alan Massey

Tony Melody as Len Fellows

Colin Meredith as Brian Burgess

Deborah Norton as Debra King

Peter Penry-Jones as Dr John Rutherford

Susan Cookson as DC Marie Snitynski

John Flanagan as Jim King

Jonathan Coy as DCS Bernard Postles

Elizabeth Bennett as Angela Woodruff

Ken Bradshaw as DS Mark Wareing

Ken Kitson as Inspector Dave Smith

David Blair as DC Mark Denham

Malcolm Raeburn as DCI Mike Williams

Rodney Litchfield as Remand Quiz Master

Jeff Nuttall as Mr Justice Forbes

Gareth Thomas as Rev Denis Thomas

Lorraine Cheshire as Canteen Lady

Bernard Wrigley as Market Trader

Marcus Romer as DC Ellis Crowther

Sarah Graham as Secretary

Jane Wood as Kath Shaw

Martin Reeve as DS Bob Hampson

Norman Mills as DC Dave O'Brien

Mark Luigi as Sgt Elwyn Jones

Carrie Davies as DC Sally Reid

Sarah Byng as Secretary

Paul Oldham as Paul Spencer

Michael Wardle as John Green

Mark Pepper as Ronald Pickford

Derek Hicks as Sgt Fullalove

Derek Hicks as DI Steve Fullalove

Alison Burrows as Julie Evans

Daryl Fishwick as WPC

Clive Bonelle as Remand Prisoner

Sally Adams as Dr Linda Reynolds

Aaron Neil as Partner

Madelaine Evans as Dr Susan Booth

Wilfred Harrison as Mr King

Demelza Randall as Debbie Bambroffe

Irene Skillington as Bereaved Woman

Michael Stainton as John Shaw

Rebecca Clay as Anne Ball

Jeff Nuttall as Mr. Justice Forbes

Garry Crystal as Journalist