
FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.
Genres:

Samuel L. Jackson as Neville Flynn

Julianna Margulies as Claire Miller

Nathan Phillips as Sean Jones

Kenan Thompson as Troy

Rachel Blanchard as Mercedes

Flex Alexander as Three G's

Keith Dallas as Big Leroy

Sunny Mabrey as Tiffany

Lin Shaye as Grace

Elsa Pataky as Maria

Bruce James as Ken

Casey Dubois as Curtis

Gerard Plunkett as Paul

Terry Chen as Chen Leong

Emily Holmes as Ashley

Mark Houghton as John Sanders

David Koechner as Rick

Bobby Cannavale as Hank Harris

Yan-Kay Crystal Lowe as Autograph Girl

Todd Louiso as Dr. Steven Price

Kendall Cross as Driver

Samantha McLeod as Kelly

Ann Warn Pegg as Mrs. Bova

Taylor Kitsch as Kyle

Kevin McNulty as Emmett Bradley

Agam Darshi as Dell Girl

Lisa Marie Caruk as Ken's Girlfriend

Mi-Jung Lee as News Anchor

Lesley Aletter as Woman Bitten on Tongue

Byron Lawson as Edward Kim

Tom Butler as Captain Sam McKeon

Chris Taloa as Sprayer (uncredited)
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