Keanu Reeves as Detective Scott Galban

Ana de Armas as Isabel de La Cruz

Mira Sorvino as Janine Cullen

Christopher McDonald as Lt. Galban

Laura Gómez as Eva

Sandy Tejada as Yesenia

Ismael Cruz Cordova as Jose de La Cruz

Big Daddy Kane as Black

Melissa Cardello Linton as Detective Ramirez

Michael Rispoli as Detective Dibronski

Denia Brache as Gloria de La Cruz

Venus Ariel as Elisa

Danny Hoch as Detective Joey Cullen

Gabe Vargas as Manuel 'Rocky' De La Cruz

Ariel R. Pacheco as Naldo

Stephen Thompson as Albino Floating Man

Clara Wong as Albino Woman

Jeanette Dilone as Marisol De La Cruz

Danny Guzman as Gucci De La Cruz

Leopold Manswell as Kendu Wallace

Justice Quiroz as Rafael

Gilbert Cruz as Grandfather

Louis Martinez as Big Pete

Amaurys Rodriguez as Rufy

Daniel Ojeda Astigarraga as Sal

Shirley Roeca as Day Care Mother

Jewel Donohue as Doctor Alain

Monte Greene as Anthony Galban

Julissa Roman as Rosa

Nelson Landrieu as Luca

Andrew Polk as Martin Himmel

Brianne Berkson as Sales Girl (uncredited)

Peter Conboy as New York City Police Officer (uncredited)

Andrea Lynn Green as Female Officer (uncredited)

Pablo Gonzalez as Munchy

Anthony Ruiz as Homeless Man