Albert Brooks as Albert Brooks

Charles Grodin as Warren Yeager

Frances Lee McCain as Jeannette Yeager

Lisa Urette as Lisa Yeager

Robert Stirrat as Eric Yeager

Dick Haymes as Councilman Harris

Matthew Tobin as Dr. Howard Hill

J.A. Preston as Dr. Ted Cleary

Mort Lindsey as Mort Lindsey

Joseph Schaffler as Paul Lowell - Realtor

Phyllis Quinn as Donna Stanley - Gift Shop Owner

James Ritz as Jack from Cincinnati

Clifford Einstein as Role Reversal Family Father

Harold Einstein as Role Reversal Family Son

Mandy Einstein as Role Reversal Family Mother

Karen Einstein as Role Reversal Family Daughter

James L. Brooks as Driving Evaluator

Zeke Manners as Driver in Evaluation

Dudley DeZonia as Andrew Felton - Alternate Family Father

Barbara DeZonia as Felton Family Member

Carolyn Silas as Felton Family Member

Adam Grant as Felton Family Member

Belle Richter as Jeanette's Mother

Jerry Jensen as Jeanette's Father

Michele Grace as Dr. Rennert's Nurse

Thelma Leeds as Margaret - Dr. Rennert's Patient

Johnny Haymer as Dr. Maxwell Rennert

Nudie as Horse Owner

Charles H. Reid as Assistant Surgeon

Susan Clark as Veterinary Nurse

Ward Rodgers as Minister

David Spielberg as Dr. Jeremy Nolan

Julie Payne as Dr. Anne Kramer

Jennings Lang as Martin Brand (voice)

Leo McElroy as Jim Sanders - Channel 5 Reporter

Carlos Jurado as Reporter

S.W. Smith as 2nd Reporter

Fred Wolfson as 3rd Reporter

Norman Bartold as Dr. Isaac Steven Hayward

Harry Shearer as Pete - Cameraman / Radio Announcer