Sidney Toler as Charlie Chan

Phyllis Brooks as Judy Hayes

Victor Sen Yung as James Chan

Eddie Collins as Al Hogan

John 'Dusty' King as Randolph

Claire Dodd as Mrs. Carol Wayne

George Zucco as Dr. Cardigan

Robert Barrat as Captain Johnson

Marc Lawrence as Johnny McCoy

Richard Lane as Joe Arnold

Ruth Clifford as Nurse

Layne Tom Jr. as Tommy Chan

Philip Ahn as Wing Foo

Paul Harvey as Inspector Rawlins

Grace Lem as Mama Chan (uncredited)