Natalie Portman as Lucy Cola

Jon Hamm as Mark Goodwin

Zazie Beetz as Erin Eccles

Dan Stevens as Drew Cola

Ellen Burstyn as Nana Holbrook

Colman Domingo as Frank Paxton

Nick Offerman as Will Plimpton

Tig Notaro as Kate Mounier

Pearl Amanda Dickson as Blue Iris

Jeffrey Donovan as Jim Hunt

Jeremiah Birkett as Hank Lynch

Stella Edwards as Chelsea

Arlo Mertz as Emily

Tobias Schönleitner as Miles Henckle

Diana DeLaCruz as Dr. Addison

Cali DiCapo as Elementary School Girl

Joe Williamson as Mayer Hines

Arnell Powell as Earl Pearly

Rene H. Herrera as Nasa Safety Diver #1

Casey Adams as Nasa Safety Diver #2

Rick Rottger as Nasa Safety Diver #3

Sean Taylor as Nasa Safety Diver #4

Shay Ali as Test Engineer

Zylan Brooks as Doctor

Jake Dashnaw as San Diego Police #1

Chad Dashnaw as San Diego Police #2

Alyma Dorsey as San Diego Police #3

Ryan Ryusaki as San Diego Police #4

Mic Rodgers as San Diego Police #5

Jay Hieron as San Diego Police #6

Brittany Berryman as Gas Station Mom

Aiden Berryman as Gas Station Boy #1

Jonny Berryman as Gas Station Boy #2

Nicole Dele as Store Clerk

Rasha Goel as News Anchor