Adam Scott as Gary Bloom

Evangeline Lilly as Samantha

Owen Atlas as Lucas

Bridget Everett as Al

Donald Faison as Larry

Chris D'Elia as Wayne

Kyle Bornheimer as Victor

Clancy Brown as Reverend J.D. Gospel

Tyler Labine as Karl C. Miller

Sally Field as Miss Shaylock

Marcus Terrell Smith as Dwayne

James Weir as Mac

Chip Zien as Stepdad Therapist

Rick Applegate as Principal

Ken Bolden as School Psychiatrist

Brad Williams as Gozamel

Allen Roth as Uncle Scott

Hank Harris as Gabriel

Carla Gallo as Wendy

Eli Craig as Derby Official

Russ Mitchell as Russ Mitchell

Paul Slimak as Homeless Albino

Schuyler White as Birthday Clown

Noah Craig as Jeremy

Mark Rademacher as Wedding Priest

Steve Kosinski as Priest

Cherie McClain as News Reporter

David Myers Gregory as End of Times Believer

Rhonda Freya English as Clerk

Peggy Miller as End Times Shopper

Sasha Williams as Mom at Waterpark

Michael Ryan Boehm as Annoyed Kid

Todd Emmett as Policeman #1

John Sundquist as Policeman #2

Ray Wise as Guy On TV (uncredited)

Kristephan Warren-Stevens as Little League Coach / Water Park Guest (uncredited)