Oscar Isaac as Mikael Boghosian

Charlotte Le Bon as Ana Khesarian

Christian Bale as Chris Myers

Daniel Giménez Cacho as Reverend Dikran Antreassian

Tom Hollander as Garin

Shohreh Aghdashloo as Marta Boghosian

Rade Šerbedžija as Stephan

Marwan Kenzari as Emre Ogan

Angela Sarafyan as Maral

Numan Acar as Mustafa

Igal Naor as Mesrob

Milene Mayer as Yeva

Tamer Hassan as Faruk Pasha

Alicia Borrachero as Lena

Abel Folk as Harut

Jean Reno as Admiral Fournet

James Cromwell as Henry Morgenthau Sr.

Kevork Malikyan as Vartan Boghosian

Lucía Zorrilla as Tamar

Roman Mitichyan as Van

Armin Amiri as Captain Ali

Stewart Scudamore as Ismet Ogan

Andrew Tarbet as Pastor Merril

Aharon Ipalé as Dr. Nazim

Shnorhk Sargsyan as Komitas

Aaron Neil as Talaat Pasha

James Chanos as General Zyniker

Anthony Rotsa as Ahmet

Michael Stahl-David as Brad

Àlex Maruny as Sharp Shooter 2

Diogo Andrade as Turkish Student (Uncredited)

Sofia Black-D'Elia as Older Yeva

Luis Callejo as Turkish Intelligence Officer

Julián Villagrán as Armenian Soldier

Alain Hernández as Turkish Telegraph Officer

Vic Tablian as Cattle Car Man

Christine Duke as Older Orphan