Steven Yeun as Bo (voice)

Gina Rodriguez as Mary (voice)

Zachary Levi as Joseph (voice)

Keegan-Michael Key as Dave (voice)

Kelly Clarkson as Leah (voice)

Anthony Anderson as Zach (voice)

Kris Kristofferson as Old Donkey (voice)

Ving Rhames as Thaddeus (voice)

Gabriel Iglesias as Rufus (voice)

Patricia Heaton as Edith (voice)

Kristin Chenoweth as Abby (voice)

Christopher Plummer as King Herod (voice)

Aidy Bryant as Ruth (voice)

Tyler Perry as Cyrus (voice)

Tracy Morgan as Felix (voice)

Oprah Winfrey as Deborah (voice)

Mariah Carey as Rebecca (voice)

Fred Tatasciore as Melchior / Inn keeper #1 / Pottery Vendor (voice)

Kari Wahlgren as Additional Voices (voice)

Gregg Berger as Inn Keeper #3 (voice)

Joel Osteen as Caspar (voice)

Lex Lang as Hunter (voice)

Roger Craig Smith as Chamberlain / Inn Keeper #5 (voice)

William Townsend as Horse / Goat (voice)

Stephen Apostolina as Additional Voices (voice)

Kirk Baily as Additional Voices (voice)

David Cowgill as Additional Voices (voice)

June Christopher as Additional Voices (voice)

Eddie Frierson as Additional Voices (voice)

Rif Hutton as Additional Voices (voice)

Mona Marshall as Additional Voices (voice)

Caitlin McKenna as Additional Voices (voice)

Scott Menville as Additional Voices (voice)

Warren Sroka as Additional Voices (voice)

Pepper Sweeney as Additional Voices (voice)

Grant George as Additional Voices (voice)

Bridget Hoffman as Additional Voices (voice)

Moira Quirk as Additional Voices (voice)

Michelle Ruff as Additional Voices (voice)

Joseph Sanfelippo as Additional Voices (voice)

Justin Shenkarow as Additional Voices (voice)

Joe Whyte as Scribe / Inn Keeper #2 (voice)