Miguel A. Núñez Jr. as Jamal Jefferies / Juwanna Mann

Vivica A. Fox as Michelle Langford

Kevin Pollak as Lorne Daniels

Tommy Davidson as Puff Smokey Smoke

Ginuwine as Romeo

Lil' Kim as Tina Parker

Dikembe Mutombo as Coyner

Vlade Divac as Morse

Muggsy Bogues as Andrew Stewart

Rasheed Wallace as Whitley

Kim Wayans as Latisha Jansen

Jenifer Lewis as Aunt Ruby

Annie Corley as Coach Rivers

Terry Loughlin as Commissioner

Bonnie Johnson as Lorne's Secretary

Tammi Reiss as Vicki Sanchez

Jay Leno as Himself

Seth Curry as Boy

Heather Burge as Self