Ronald Colman as Robert " Bob " Conway

Jane Wyatt as Sondra Bizet

Edward Everett Horton as Alexander P. " Lovey " Lovett

John Howard as George Conway

Thomas Mitchell as Henry Barnard

Margo as Maria

Isabel Jewell as Gloria Stone

H.B. Warner as Chang

Sam Jaffe as High Lama

John Burton as Wynant (uncredited)

Milton Owen as Fenner (uncredited)

John T. Murray as Meeker (uncredited)

Victor Wong as Bandit Leader (uncredited)

Carl Stockdale as Missionary (uncredited)

David Torrence as Prime Minister (uncredited)

Wedgwood Nowell as Englishman (uncredited)

Richard Loo as Shanghai Airport Official (uncredited)

Margaret McWade as Missionary (uncredited)

Willie Fung as Bandit Leader at Fuel Stop-over (uncredited)

George Chan as Chinese Priest (uncredited)

Wyrley Birch as Missionary (uncredited)

Norman Ainsley as Embassy Club Steward (uncredited)

David Clyde as Embassy Club Steward (uncredited)

Noble Johnson as Leader of Porters (uncredited)

Chief John Big Tree as Porter (uncredited)

Harold Lishman as Porter (uncredited)