Holly Hunter as Eleanor Weller

Alfred Molina as Paul Weller

Cristin Milioti as Maud Weller

Tony Shalhoub as Adam Weller

Maggie Wagner as Melanie

Omar Metwally as Samir Kamali

Caroline Aaron as Judith Singer

Brooke Adams as Ruth Frank

Beege Barkette as Joanne

Isabelle Candelier as Sandrine Bonhommet

Adrian Lester as Ken Yates

Siena Marino as Zahra

Celia Keenan-Bolger as Jenny

Tamika Lawrence as Tara

Carl Lundstedt as Waiter

Peter O'Meara as Brian Galvin

Barry Primus as Dr. Chazen

Jeremy Shamos as Robert Gordon

Gameela Wright as Louise