Morena Baccarin as Gamemaster (voice)

William Shatner as The Overseer (voice)

Ray Wise as Cyrus DeKalb (voice)

Bill Moseley as Pavel (voice)

Florence Hartigan as Kelsy DeKalb (voice)

Damien C. Haas as Ethan DeKalb (voice)

Mark Whitten as Walt, Razor Sharp (voice)

Dani Lennon as Miriam DeKalb (voice)

Jason Axinn as Additional Voices (voice)

Mark Whitten as Walt, Roaring 20s Gambler (voice)

Benjamin Siemon as Collin DeKalb (voice)

Bill Millsap as Clay, Senator Thomas Otterman (voice)

Jim Cirile as Barbarian Gambler, Buzzcut Psychopath (voice)

Tanya C. Klein as 80s Gambler (voice)

Tom Lommel as Det. Lang, Roman Gambler (voice)

Paige Barnett as Victorian Gambler (voice)

Steve Geiger as Jurek (voice)

Charles Wyman as Cop 3 (voice)

Ruairí Douglas as Aengus O'Callaghan (voice)