Amanda Seyfried as Sophie

Christopher Egan as Charlie

Gael García Bernal as Victor

Vanessa Redgrave as Claire

Franco Nero as Lorenzo

Luisa Ranieri as Isabella

Milena Vukotić as Maria

Marina Massironi as Francesca

Marcia DeBonis as Lorraine

Luisa De Santis as Angelina

Paolo Arvedi as Signor Ricci (Olive Farmer)

Lidia Biondi as Donatella

Dario Conti as Cheese Supplier

Giordano Formenti as Viticoltore

Remo Remotti as Farm House Lorenzo

Ivana Lotito as Young Girl

Angelo Infanti as Chess Playing Lorenzo

Giacomo Piperno as Lorenzo on Lake

Fabio Testi as Count Lorenzo

Sara Armentano as Folks Home Nurse

Benito Deotto as Folks Home Lorenzo

Marcello Catania as Take Him Lorenzo

Silvana Bosi as Take Him Lorenzo's Wife

Elio Veller as Grocer Lorenzo

Sandro Dori as Priest Lorenzo

Adriano Guerri as Waiter Lorenzo

Stefano Guerrini as Lorenzo - Grandson

Daniel Emilio Baldock as Lorenzo - Father

Robbie Neigeborn as Sign Maker

Hilary Edson as Receptionist

Ashley Lilley as Patricia

Peter Arpesella as American Tourist (voice) (uncredited)

Ginevra Iorio as Lorenzo - Little Granddaughter (uncredited)

Laura Jane Jones as Singer - soloist (uncredited)

Gabriele Manfredi as Lorenzo - Grandson (uncredited)

Oliver Platt as New Yorker Magazine Editor Bobby (uncredited)

Antonio Randazzo as Delivery Man (uncredited)

Uzimann as Hot Dog Vendor (uncredited)