Maisie Williams as Skye

Asa Butterfield as Calvin

Nina Dobrev as Izzy

Tyler Hoechlin as Frank

David Koechner as Bob

Peyton List as Ashley

Tituss Burgess as Julian

Sonya Walger as Claire

Margot Bingham as Lucy

Ken Jeong as Officer Al

Colin Moss as Greg

Briana Venskus as Officer Mya

Ron Simons as Dr. Collins

Angel Valle Jr. as Will

L. Steven Taylor as Dan

Francesca Noel as Hannah

Ann Osmond as Ellen

Crystal Tweed as Oncologist

Ashlyn Alessi as Party Girl (uncredited)

Billy Thomas Myott as Party Kid (uncredited)