Martin Starr as Joe Larsen

Mae Whitman as Emily Klein

Nat Faxon as Gregg

Cameron Esposito as Chloe Johnston

Retta as Pauline 'Roger' Rogers

Christine Lahti as Beth Larsen

Kris D. Lofton as Dean

Kate Cobb as Meghan

Tim Hopper as Fisherman

Abigail Boucher as Doctor

Bilal Dardai as Bilal

Trevor Dawkins as Trevor

Kelley Dorney as Patient Who Wants To Keep Her Doctor

Nick Hart as Nick

Phil Ridarelli as Hostile Guest

Kirsten Riiber as Wynn

Heather Riordan as Woman Who Wants New Sheets

Leah Urzendowski as Leah

Asif Ali as Embarrassed Guy's Voice (voice)

Caroline Kwan as Yoga Instructor