Taraji P. Henson as Katherine G. Johnson

Octavia Spencer as Dorothy Vaughan

Janelle Monáe as Mary Jackson

Kevin Costner as Al Harrison

Kirsten Dunst as Vivian Mitchell

Jim Parsons as Paul Stafford

Mahershala Ali as Jim Johnson

Glen Powell as John Glenn

Ariana Neal as Joylette Johnson

Saniyya Sidney as Constance Johnson

Zani Jones Mbayise as Kathy Johnson

Donna Biscoe as Joylette Coleman

Olek Krupa as Karl Zielinski

Aldis Hodge as Levi Jackson

Kimberly Quinn as Ruth

Frank Hoyt Taylor as Judge

Lidya Jewett as Young Katherine

Karan Kendrick as Younger Joylette

Jaiden Kaine as Joshua Coleman

Kurt Krause as Sam Turner

Ken Strunk as Jim Webb

Selah Kimbro Jones as Carolyn Marie Jackson

Tre Stokes as Levi Jackson Jr.

Corey Mendell Parker as Howard Vaughan

Ashton Tyler as Leonard Vaughan

Alkoya Brunson as Kenneth Vaughan

Ron Clinton Smith as White Cop

Gregory Alan Williams as Marion Smithson

Maria Howell as Ms. Sumner

Arnell Powell as Professor Graves

Crystal Lee Brown as Bernie

Tequilla Whitfield as Eleanor

Dane Davenport as Alan Shepard

Evan Holtzman as Deke Slayton

Travis Smith as Scott Carpenter

Scott Michael Morgan as Bill Calhoun

Chris Cavalier as IBM Technician

Robert G. McKay as Pastor Ayres

Rhoda Griffis as White Librarian

Karen Wheeling Reynolds as Court Clerk

Kate Kneeland as Court Clerk

Joe Knezevich as Wind Tunnel PA Announcer

Paul Ryden as TV Reporter at Cape Canaveral

John Atwood as Newscaster

Jon Edwin Wright as Newscaster

Wilbur Fitzgerald as Senator Patrick

Michael Hartson as Night School Professor

Bob Jennings as Navy Officer

Gary Weeks as Reporter at Press Conference

Afemo Omilami as Man Outside Store

Cullen Moss as Mission Control Commander

Amy Tipton as Woman Crying

Elijah Everett as Man Crying

Andre Pushkin as Russian Scientist

Randall Newsome as Russian Scientist

Joe Hardy Jr. as Gordon Cooper

Howie Johnson as Library Security Guard

David Kallaway as NASA Security Guard

Addison Rose Melfi as Addie Marcus

Paige Nicollette as Eunice (uncredited)