Dany Boon as François Gautier

Laurence Arné as Valérie

Noémie Schmidt as Laura

Patrick Ridremont as Cédric

Karina Marimon as Carole

Nicolas Lumbreras as Rémy, banquier

Christophe Canard as Gilles, violoniste

Christophe Favre as Demeester, chef d'orchestre

Stéphan Wojtowicz as Président du syndic

Anne-Sophie Girard as Sophie, contrebassiste

Monique Mauclair as Voisine

Laurent Saint-Gérard as Serveur du restaurant chic

Laurent Fernandez as Loïc, patron de la crêperie

Pierre Diot as Musicien dans le plâtre

Benoît Tachoires as Curé

Pierre Benoist as Professeur, cagnotte retraite

Charline Paul as Mère de François

Jérémy Lopez as Père de François

Sacha Petronijevic as Médecin

Jean-Luc Porraz as Professeur retraité

Noël Lafon as Mari de la voisine

Jacques Marchand as Voisin

Lisa Spurio as Carole (22 ans)

Matthieu Kassimo as François Gautier (20 ans)

Emmanuelle Rivière as Gwenaëlle, patronne crêperie

Amaury Breton as François Gautier (13 ans)

Gavril Dartevelle as François Gautier (7 ans)

Christine Bonnard as Femme du banquier

Claire Beaugé as Caissière

Catherine Giron as Dame supermarché

Laure Sirieix as Infirmière Maternité

Jean Marc Le Bars as Traiteur

Victor Ghesquière as Gaëtan, élève violon