Oakes Fegley as Ben

Millicent Simmonds as Rose

Julianne Moore as Lillian Mayhew / Rose

Michelle Williams as Elaine

Cory Michael Smith as Walter

James Urbaniak as Dr. Kincaid, Rose's Father

Damian Young as Otto, Museum Guard

Patrick Murney as Workman

Lauren Ridloff as Pearl, The Maid

Anthony Natale as Dr. Gill, Teacher of the Deaf

Carole Addabbo as Miss Conrad at the Museum

Howard Seago as Remy Rubin, Theater Director

Brian Berrebbi as Stage Manager

John P. McGinty as Valentin

Mark A. Keeton as Shopkeeper

Patrick Wiley as Window Dresser

Garrett Zuercher as Officer Engel

Jared Johnston as Officer Murtha

Murphy Guyer as Security Chief

Ekaterina Samsonov as Hannah

Sawyer Niehaus as Blessing

Lilianne Rojek as Florence

Michael W. Gaines as Butler

Jaden Michael as Jamie

Tom Noonan as Walter

Morgan Turner as Janet

Amy Hargreaves as Aunt Jenny

Sawyer Nunes as Robbie

Raul Torres as Jamie's Father

Mandela Bellamy as Woman on Bus

Jim Lavin as ER Doctor

Colleen Cosgrove as ER Nurse

Hays Wellford as Greg Coons at the Bus Stop

Asa Liebmann as Thief

John Boyd as Danny

Oladamolami Adisa as Signing Hands

Mylo Barrett as Signing Hands

Robinho Cruz as Signing Hands

Vanessa DeLeon as Signing Hands

Jordana Lurman as Signing Hands

Tom Waters as 1970's Business Man (uncredited)

Connor Moeller as Museum Boy (uncredited)

Mackenzie Grace Castle as Museum Girl (uncredited)

Derek Chadwick as Liam (uncredited)

Logan Taylor as Promenade Child / Museum Child (uncredited)