Hugh O'Brian as Wyatt Earp

Bruce Boxleitner as Sam, Sheriff of Cochise County

Paul Brinegar as Jim 'Dog' Kelly

Harry Carey, Jr. as Digger Phelps

Bo Hopkins as Rattlesnake Reynolds

Alex Hyde-White as Woodworth Clum

Martin Kove as Ed Ross

Don Meredith as Clay the Bartender

Jay Underwood as Jack Montgomery

Douglas Fowley as Doc Holliday / Doc Fabrique (flashback sequences) (archive footage)

John Anderson as Virgil Earp (flashback sequence) (archive footage)

Steve Brodie as Sheriff John Behan (flashback sequence) (archive footage)

Lloyd Corrigan as Ned Buntline (flashback sequence) (archive footage)

Gordon Wynn as Colonel Warren (Flashback Sequence)