Sidney Toler as Charlie Chan

Joan Woodbury as Leah Manning

Mantan Moreland as Birmingham Brown, Taxi Driver

Benson Fong as Tommy Chan, #3 Son

Ian Keith as Dr. Paul Recknik

Sam Flint as Thomas P. Manning

Cy Kendall as George Webster Deacon

Weldon Heyburn as Detective Lt. Harvey Dennis

Anthony Warde as Catlen

John Davidson as Carl Karzoff / Kurt Karzoff

Dewey Robinson as Salos

I. Stanford Jolley as Gannet

Betty Blythe as Mrs. Manning

Jack Norton as Hotel Desk Clerk

Luke Chan as Wu Song