Karl Michael Vogler as Christoph Kolumbus

Udo Vioff as Amerigo Vespucci

Joseph Offenbach as Kanzler Santangel

Klaus Schwarzkopf as José Vendrino

Maria Sebaldt as Marchesa Beatrice de Moya

Margot Trooger as Königin Isabella

Theo Lingen as König Ferdinand

Harry Wüstenhagen as Quintanilla

Walter Hoor as Pepi damals

Hans Clarin as Pepi heute

Hannelore Elsner as Anacoana

Edgar Hoppe as Diego

Gernot Duda as Rodrigo

Michael Habeck as Dicky

Henning Schlüter as Koch

Benno Hoffmann as Medizinmann

Herbert Weißbach as Steuerbeamter

Friedrich Maurer as Erzbischof