Jessica Chastain as Catherine Weldon

Michael Greyeyes as Sitting Bull

Sam Rockwell as Silas Groves

Ciarán Hinds as James McLaughlin

Chaske Spencer as Chaska

Bill Camp as General Crook

Willy RunsAbove as Chief Black Bear

Louisa Krause as Loretta

Robert Mirabal as Only Man

Monika Crowfoot as Seen By The Nation

David Midthunder as Shell King

Rulan Tangen as Susan McLaughlin

Robert Moreno Sr. as Thunder

Ben Ziegler as Attacker in Cannonball

Boots Southerland as Cab Driver NY

Ben Black Bear as Chief

Rachel Singer as Dry Goods Assistant

Andersen Kee as Indian Policeman

Cosme Duarte as Indian Policeman

Rod Rondeaux as Indian Robber

Luce Rains as Old Man at Train Station

Debbie Black Lance as Old Sioux Woman

Makayah Starley Crowfoot as Sioux Child

DezBaa' as Sioux Woman at Ration Day

Lyle Sandoval as Tracker

Jacob Browne as Waiter in Dining Car

Kindall Charters as Waiter in Sleeping Car

Susan Conklin as Woman in Cannonball

Brenda Wehle as Anna Maria Valentine (uncredited)

David Hight as Cavalry Lt. (uncredited)

Josh Outzen as Cavalry Soldier (uncredited)

Lyle DeRose as Cavalry Soldier (uncredited)

Rip Lowe as Cavalry Soldier (uncredited)

Philip David Pickard as Colonel (uncredited)

Rodrigo Tactaquin as Ghost Dancer (uncredited)

Manny Greenfield as Government Official (uncredited)

Rick Tadra as Government Offical (uncredited)

Michael Nouri as Karl Valentine (uncredited)

Claire Weinstein as Native Woman (uncredited)

Andrea Good as Native Villager (uncredited)

Denita Wolf as Townsperson (uncredited)

Richard Beal as Townsperson (uncredited)

Stephen Conn as Townsperson (uncredited)

Tami Nichols Reilly as Townsperson (uncredited)