Grey DeLisle as Dorothy (voice)

Joe Alaskey as The Wizard of Oz / Butch / Droopy (voice)

Michael Gough as The Scarecrow / Hunk (voice)

Rob Paulsen as The Tin Man / Hickory (voice)

Todd Stashwick as The Cowardly Lion / Zeke (voice)

Frances Conroy as Auntie Em / Glinda (voice)

Stephen Root as Uncle Henry (voice)

Kath Soucie as Tuffy the Munchkin Mouse / Tractor (voice)

James Monroe Iglehart as Calvin Carney / Jitterbug (voice)

Amy Pemberton as Dorothy / The Mouse Queen (voice)

Laraine Newman as The Wicked Witch of the West (voice)

Andrea Martin as The Hungry Tiger (voice)

Jason Alexander as Mr. Bibb / The Nome King (voice)

Spike Brandt as Spike (voice)

Jye Frasca as Gnome (voice)