Johnny Depp as Sam

Mary Stuart Masterson as Juniper 'Joon' Pearl

Aidan Quinn as Benjamin 'Benny' Pearl

Julianne Moore as Ruthie

Oliver Platt as Eric

CCH Pounder as Dr. Garvey

Dan Hedaya as Thomas

Joe Grifasi as Mike

William H. Macy as Randy Burch

Liane Curtis as Claudia

Eileen Ryan as Mrs. Smail

Lynette Walden as Female Customer

Waldo Larson as Waldo

Don Hamilton as UPS man

Leslie Laursen as Admitting Nurse

John Grant Phillips as Policeman

Irvin Johnson as Orderly

Shane Nilsson as Orderly

Faye Killebrew as Video Customer

Ramsin Amirkhas as Video Clerk

Amy Alizabeth Sanford as Young Joon

Brian Keevy as Young Benny

Tony Lincoln as Local

Noon Orsatti as Patron

Dan Kamin as Patron

Gregory Cook as Guy in the Park (uncredited)

Aaron Haedt as Bicyclist (uncredited)